"Let no one deceive you by any means; for that Day will not come unless the falling away comes first, and the man of sin is revealed, the son of perdition"
2 Thessalonians 2:3
Paul promises us that the Great Day of the Lord will not come until the 'falling away comes first.'
Other prophecies also warn about the religious apostasy of the last days.
The Antichrist will only be revealed at the appropriate time after God removes His restraining power.